To Pastor, Afterlife Is Where We 'Learn To Live Together'

Detail of the central compartment of The Adoration of the Mystic Lamb, completed in 1432 by Jan van Eyck, where pilgrims gather to pay homage to the lamb of God. Many art historians interpret the painting's fountain as a symbol of eternal life.

DEA Picture Library/De Agostini/Getty Images

A majority of Americans from all walks of life believe in life after death. Yet conversations about the afterlife — from what it might look and feel like to who else one may find there — often remain highly personal ones, shared with family members, clergy or others who share one's faith.

To better understand how many Americans conceive of the afterlife, All Things Considered has spoken with leaders from different faith traditions on their views on life after death.

First, an evangelical Protestant's perspective. The Rev. Gabriel Salguero, a pastor of The Lamb's Church in New York City and president of the National Latino Evangelical Coalition, tells NPR's Robert Siegel how faith in the afterlife informs Salguero's life and why he sees heaven as a place where diverse people coexist without the tensions that sometimes divide them on earth.

Interview Highlights

On what he expects heaven might be like:

The faith of my childhood ... talked about a heaven where there was no sickness, no disease, no hate, no crime, no evil. And I very much still cling to that eternity of heaven where we as people have learned to live together, despite difference and despite our cultural backgrounds. So whether that's a distant place beyond the galaxies or a renewed earth where the kingdom of God and the reign of God is, I think that's what's most important. ...

Revelation has these beautiful images — and of course ... I interpret most of it metaphorically, right, not literally — it talks about us eating and playing and singing and chatting and having relationships. Jesus, when he talks about preparing a place for us, you know, he often talks about us talking and eating. After the Resurrection in the New Testament narratives, the first thing Jesus does is actually ask for food in his resurrected body. He says, "Hey, where's the bread, where are the fish?"

So I think it's a vision of a corporal reality where we finally learn to be reconciled with God and each other.

On his views on ethnic or racial identity and the afterlife:

What Revelation says, particularly in chapter 7, ... says, "From every tribe, nation, and tongue." I don't think eternity does away with difference. I think we're going to see people's race, culture, in eternity.

What I think it does is it reconciles it. Where it says, "I'm Hispanic, I'm Latino." And I'm going to see African-Americans, and I'm going to see whites, and I'm going to see Asians in heaven. And I think that phenotype will be there. I would be saddened if difference was obliterated in eternity. I think they're just going to be reconciled and we're going to learn, finally, to live together. ...

I think what God is calling us [to], and particularly as a Christian, is right relationships. And for me that's done through the person of Jesus Christ. A right relationship with God here on earth, and also in eternity. So I'm gonna see people from across the geographic spectrum, and across the racial/cultural spectrum.

On how belief in eternity can inform life on earth:

I think that the calling of eternity, for me — and even as I preach to my parishioners, which is a very multiethnic congregation — what I tell them is, that the view of eternity should serve as an ethical imperative. Or, in the words of Jesus of Nazareth in his prayer, "Let your kingdom come, let your will be done, on earth as it is in heaven."

So heaven, ... the view of eternity, is a template for moral relationships here on earth. It's a calling to our higher angels, if you will.

On how he would live his life if he didn't believe in eternity:

If there were no eternity ... I think the teachings of Jesus would be enough for me. He lived a moral life. He told us, "Love our neighbor, forgive our enemies, bless those who persecute you." That's enough. That's the highest teaching I've ever encountered.

But, fortunately enough, it's not an either-or, but a both-and. There is an eternity, from where I sit, and the teachings of Jesus are enough.

All Things Considered is collecting stories all week about what you think happens when you die. To join the conversation, please use the comments below or send a message on Twitter, Tumblr or Facebook using the hashtag #nprafterlife.

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NASA Satellites Can Even Make a Devastating Drought Look Incredible

Watching the animation above, it's hard not to get goosebumps when the the clock hits 2012 and the whole United States goes red. That's what it looks like from space when the Earth is parched.

Read more...

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/3RiBEzKwiNc/nasa-satellites-can-even-make-a-devastating-drought-loo-1108974715

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Scientists: Supplemental red snapper season likely in Gulf of Mexico

Scientists say one of the most popular fish in the Gulf of Mexico has rebounded enough to allow a second season for red snapper this year.

The Gulf of Mexico Fishery Management Council meets in New Orleans on Wednesday to consider increased fishing quotas and a supplemental 2013 season for red snapper, one of the region's most popular game and eating fish.

Click to read more.

Source: http://www.nbcnews.com/id/52490570/ns/local_news-new_orleans_la/

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BAKKEN SHALE: N.D. GDP blows past national average thanks to oil boom

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Source: http://www.eenews.net/energywire/stories/1059984341/feed

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Elon Musk Will Reveal His High-Speed Hyperloop Transport Design By August 12

Startup renaissance man Elon Musk has spent the past year or so not-so-subtly dropping hints about yet another ambitious transport project of his, and it seems he's getting ready to describe it in more detail. Amid plenty of speculation, Musk revealed in a tweet earlier today that he plans to publish his tentative designs for the Hyperloop system by August 12.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/e4ARwjTUAbk/

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'The Lion King' on the road hits $1 billion

NEW YORK (AP) ? It's a mainstay on Broadway and now "The Lion King" has proved it's a king on the road, too.

Disney Theatrical Productions said Wednesday that the show's total touring box office gross in North America has reached $1 billion. Producers estimate that more than 15 million theatergoers in over 70 cities across North America have seen the show since 2002.

Says Jack Eldon, a vice president at Disney Theatrical Productions: "We remain overwhelmed by the enduring response to the show and are enormously thankful to our patrons ? new and returning ? for their continued enthusiasm and support."

It reached its milestone quickly. Three national tours of "The Phantom of the Opera" have grossed over $1.5 billion in combined box office sales but the first kicked off in 1989.

Source: http://news.yahoo.com/lion-king-road-hits-1-billion-212254050.html

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Coatings have simple recipe for success

Cheap approach, natural ingredients may prove useful in foods, medicines

By Rachel Ehrenberg

Web edition: July 11, 2013

Enlarge

COATS AFLOAT

Mix iron and tannic acid in water and they'll bond, forming little capsules (shown), scientists have discovered. The process is quick, easy and reversible.

Credit: Courtesy of Science/AAAS

It?s not often that chemists find a quick, simple and cheap method for making things using widely available ingredients, but researchers have done just that: They?ve created elegant little capsules and coatings in water simply by mixing iron and a compound from plants called tannic acid. The soft coatings form on their own around whatever else is in the water ? glass beads, bacteria, gold nanoparticles and more. Just changing the solution?s pH can prompts the coatings to disassemble.

The coatings? ingredients are considered safe ? tannic acid is found in wine, while iron is an important element for living things. That means the capsules might help in delivering drugs in the body or find use in cosmetics or foods, says bioengineer Gregory Payne of the University of Maryland in College Park.

The work fits with an ongoing effort to find biologically friendly, useful materials, Payne says, and it takes advantage of materials that are right under everyone?s noses. ?It opens up a lot of opportunities.?

Using ordinary lab equipment, the research team, led by materials scientist Frank Caruso of the University of Melbourne in Australia, create the tiny coatings at room temperature. When the researchers add tannic acid to water, it tends to congregate around surfaces, whether they be a piece of polystyrene or an E. coli bacterium. When the researchers add iron ions to the mix, the iron latches onto the tannic acid molecules, connecting them into a thin film. At a pH of 7.4, the capsules were still intact after 10 days; at a pH of 3, they disassembled within four hours, the team reports in the July 12 Science.

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Suggested Reading

W.E. Bentley and G.F. Payne. Nature?s other self-assemblers. Science. Vol. 341, July 12, 2013, p.136. doi:10.1126/science.1241562. [Go to]

R. Ehrenberg. Microsculptures made easy. Science News Online, May 16, 2013. [Go to]

D. Castelvecchi. Hooking up. Science News. Vol. 172, November 10, 2007, p.301. [Go to]

Source: http://www.sciencenews.org/view/generic/id/351501/title/Coatings_have_simple_recipe_for_success

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Zimmerman Trial Day 11: Live Video, Analysis of ... - Legal Insurrection

Today we will again be covering the Zimmerman Trial live, all day, with streaming video. Continuing commentary will be posted in the Twitter feed of selected contributors below the first video feed, and breaking news will be added at the bottom of this post.

Live Stream Video

WITH COMMENTARY FROM CHANNEL 9 IN SANFORD

[For live-stream video without commentary, see NBC live feed at bottom of this post.]

Twitter Feed:

(My tweets can be identified as coming from @lawselfdefense, or @lawselfdefense2 if I?m in Twitmo?follow both!.)

Live Stream Video Alternative

LIVE-STREAM WITHOUT COMMENTARY FROM NBC

Tuesday, July 9 Commentary

During the lunch recess, or immediately thereafter, we will TRY topost a mid-day update. We?ll then follow up with the usual detailed end-of-day wrap up, including video and embedded Tweets, at the usual time in the evening.

Our end-of-day wrap-up and analysis of yesterday focused on the collapse of the State?s ?scream? theory of the case, which imploded with the disclosure that Tracey Martin had initially denied that the screaming on the Lauer 911 recording was that of his son, Trayvon Martin. It also noted that the Court had decided to allow Trayvon Martin?s toxicology report to be allowed into evdience. Also, of course, it contains video of all the other testimony and hearings caught on camera throughout the day. That can be found here:

Implosion: Police Testify Trayvon?s Father Originally Denied Son Was Screaming

This past weekend I posted up an analytical piece of Mark O?Mara?s request for a judgment of acquittal. O?Mara?s motion was well-reasoned and supported by Florida?s case law. It was, of course, doomed to peremptory denial by Judge Nelson. In that piece I?ve linked almost all of the case citations made by O?Mara to full-length copies of the decisions, so you can see the sources for yourselves, if you like (most of the decisions are gratifyingly brief). You can see that here:

Why Zimmerman?s Motion for Acquittal Should Have Been Granted

Last Thursday, July 4, I had posted up a review of the trial to date, with some prognostication of how things may role out in the coming days. To take a look at that, click here:

Zimmerman Trial Review? How We Got Here, And Where We?re Going

For all of our prior coverage on day-to-day events in court, as covered here at Legal Insurrection, click here:

ARCHIVE: Zimmerman Trial LIVE coverage all day, every day

For all of our prior coverage on issues specific to the Law of Self Defense as covered at my own blog, click here:

Law of Self Defense Blog: Zimmerman Trial

(NOTE: If you do wander over to the LOSD blog, be sure to come back to Legal Insurrection to comment, as nearly all my time is spent here for the duration of the trial.)

---

Andrew F. Branca is an MA lawyer and author of the seminal book ?The Law of Self Defense,? now available in its just released 2nd Edition, which shows you how to successfully fight the 20-to-life legal battle everyone faces after defending themselves. Take advantage of the 20% ?Zimmerman trial? discount & free shipping (ends when the jury returns a verdict). NRA & IDPA members can also use checkout coupon LOSD2-NRA for an additional 10% off. To do so simply visit the Law of Self Defense blog. (Coupon works ONLY at www.lawofselfdefense.com.)

Note also that ?The Law of Self Defense, 2nd Edition? is also available at Amazon.com. ?They set their own price, and it can vary each day, so you might want to check there to see if they are offering the best deal today.

Many thanks to Professor Jacobson for the?invitation to guest-blog on the Zimmerman trial here on Legal Insurrection!

You can follow Andrew on Twitter on @LawSelfDefense?(or @LawSelfDefense2 if I?m in Twitmo, follow both!) on Facebook, and at his blog, The Law of Self Defense.

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Zimmerman Trial Day 11: Live Video, Analysis of Defense?s Case & Witnesses

62 votes, 3.89 avg. rating (77% score)

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Source: http://legalinsurrection.com/2013/07/zimmerman-trial-day-11-live-video-analysis-of-states-case-witnesses/

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California Prisons Illegally Sterilizing Female Inmates as Recently as 2010

A room in the former hospital on California's Alcatraz Island.

Photo by Justin Sullivan/Getty Images

Although it never got the kind of coverage that abortion rights did, forced sterilization was another reproductive rights violation that plagued women in the 20^th century. The practice gradually disappeared as the concept of reproductive autonomy took hold in our national consciousness. Or we thought it did. But a new report from the Center for Investigative Reporting?suggests that as recently as 2010, California prisons were coercing women into permanent sterilization by skipping over protocols put in place to prevent such coercion.

In California, a health care committee is supposed to authorize prisoner tubal litigations in order to prevent abuses, but from 2006 to 2010, 148 women were sterilized by doctors who just skipped that step. CIR says there may be as many as 100 more cases dating back to the 1990s.?

CIR interviewed doctors who were involved in sterilizations in California prisons, and comments from these doctors only raise suspicion that they supported a system of bullying and frightening women into agreeing to sterilizations they did not want. Dr. James Heinrich is accused by at least one inmate of badgering her about sterilization until she caved, and his comments about the money spent by the state on these procedures are not very reassuring.?

?Over a 10-year period, that isn?t a huge amount of money,? Heinrich said, ?compared to what you save in welfare paying for these unwanted children?as they procreated more.?

"Unwanted" by whom? The women themselves or Heinrich? Christina Cordero, who was sterilized by Heinrich, says she wished she hadn't had the tubal litigation. So perhaps any child she might have conceived would have been wanted.

Another doctor who worked for the California prison system was recorded spouting right-wing urban legends about people who "want" to be in prison for the supposedly great health care.?

The top medical manager at Valley State Prison from 2005 to 2008 characterized the surgeries as an empowerment issue for female inmates, providing them the same options as women on the outside. Daun Martin, a licensed psychologist, also claimed that some pregnant women, particularly those on drugs or who were homeless, would commit crimes so they could return to prison for better health care.

?Do I criticize those women for manipulating the system because they?re pregnant? Absolutely not,? Martin, 73, said. ?But I don?t think it should happen. And I?d like to find ways to decrease that.?

Any comment that implies that certain kinds of people don't yearn for freedom should be viewed with suspicion, but especially under the circumstances. After all, as CIR reports, U.S. District Judge Thelton Henderson of the Northern District of California ruled in 2006 that the health care system in the area prisons was so bad it constituted a human rights violation. The claim that women are routinely trading in their freedom and their families just to get access to such a shoddy level of care is pretty hard to swallow.?

Incarcerated women deserve to have access to contraception, of course, and plenty of women are interested in long-term solutions. No one denies this, but CIR's report?shows how "access" can turn into "coercion" very quickly when the women in question are marginalized or imprisoned. The frustrating part is that California already has fail-safes to make sure that line is not crossed, but the rules only work if you actually bother to follow them.?

Source: http://www.slate.com/blogs/xx_factor/2013/07/08/california_prisons_have_been_illegally_sterilizing_female_inmates.html

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Mexico opposition leads in Baja California, boosting reform pact

By Dave Graham and Luc Cohen

MEXICO CITY (Reuters) - Mexico's opposition conservatives were heading for victory in a regional election early on Monday, likely bolstering a fragile national cross-party pact forged to broker economic reforms.

Nearly half of Mexico's 31 states held elections on Sunday for a mix of local parliaments and municipal governments, but the focus was on the race for governor in Baja California, a stronghold of the conservative National Action Party (PAN).

Both the PAN and President Enrique Pena Nieto's Institutional Revolutionary Party (PRI) claimed victory in the state after polls closed, but an initial vote count showed the conservatives maintaining a narrow but consistent lead.

With nearly 96 percent of the ballots counted, the PAN had an advantage of 3 percentage points over the PRI, or 47.2 percent of the vote, preliminary results from the local electoral authority showed.

The Baja California vote has been under close scrutiny because a defeat for the PAN was expected to rattle the "Pact for Mexico" that Pena Nieto made with opposition leaders to strengthen his hand in Congress, where the PRI lacks a majority.

A victory for the PAN could prove more useful to Pena Nieto than a win for his own party if it helps strengthen the political accord he unveiled after taking office in December.

The PAN lost control of Mexico in last year's presidential elections and it is now the third force in Congress. But Pena Nieto needs to keep the conservatives on board to push through planned overhauls of state oil giant Pemex and the tax system.

Those two reforms are due to be presented by early September, and Pena Nieto is keen to secure as much political support for them as possible, particularly as the Pemex shake-up is likely to face stiff opposition from the left.

Before results came in, Manlio Fabio Beltrones, the PRI's leader in the lower house of Congress, encouraged the parties not to dwell on the outcome of Sunday's elections.

"Once election day has passed, we need to focus on the pending legislative work," Beltrones said.

VIOLENCE

Baja California is one of the PAN's few remaining bastions, and the first state it captured from the PRI 24 years ago. It proved a major stepping stone to the PAN claiming the presidency in 2000 after 71 consecutive years of rule by the PRI.

Throughout the election campaign, PAN lawmakers accused the PRI of trying to fix the outcome by buying votes, and they warned that any sign of fraud could scuttle the national pact.

Outside of the gubernatorial contest, partial results in major mayoral races showed the PAN looked set to take city hall from the PRI in Mexicali, Saltillo and Aguascalientes.

By contrast, the PRI led in Oaxaca and other rural strongholds, as well as the populous Gulf state of Veracruz.

A few hours before the polls closed, Madero was asked how he viewed the future of the Pact, and said: "the need to reach agreements is still there, it's still imperative for Mexico."

The PAN's image has been hurt by public infighting since last year's national election defeat, when voters punished the party for failing to curb violence between warring drug cartels that has claimed more than 70,000 lives since 2007.

The bloodshed has continued under Pena Nieto's rule and the campaign for the July 7 elections was marred by the murder and kidnapping of a number of candidates.

The Baja California election was also deemed to be crucial for Madero's continuing leadership of the PAN. Any battle for control of the party could threaten the pact, which has already pushed a big education reform and a shake-up of competition in the telecoms sector through Congress.

But the central planks of Pena Nieto's hopes to raise economic growth to 6 percent a year from an average of barely 2 percent since the millennium began are reforms to bolster tax revenues and open up Pemex to more private investment.

Those measures may be in doubt if the pact falls apart.

(Additional reporting by Michael O'Boyle and Tomas Sarmiento; Editing by Bill Trott)

Source: http://news.yahoo.com/mexico-opposition-leads-baja-california-boosting-reform-pact-130012693.html

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Luke Hancock Selected As USA Flag Bearer At ... - Card Chronicle

Some very patriotic news to share on this Fourth of July as Louisville's own Luke Hancock has been selected to be the flag-bearer for the United States during Saturday's opening ceremonies for the World University Games in Russia.

Hancock was selected out of more than 280 American athletes.

"That's a pretty cool feeling," Hancock said. "It will be a great moment that I'll be able to bring back with me."

The Final Four's Most Outstanding Player, Hancock turned heads nationally by playing inspired basketball in front of a father who was battling cancer. His father lost that battle last month, but not before he knew that his son would be trying out for the USA Basketball team.

"Everybody's excited when they get an invitation like this, to come play for their country," Hancock said. "I talked to my dad before I left. We talked about this. This is where he wanted me to be and this is kind of how my family wanted me to go through with it. I thought about not going, just staying home. But my dad made sure that I went. He made sure that I at least tried. It's been a rough week, but this is where he wanted me to be I guess.

"When I heard I made the team it was a pretty proud moment. But it was also a very tough moment because I couldn't call home and tell my dad. But my mom (Van) and I had a moment. This has been great for me and my family. It's kind of lifted everybody up just a little bit.

"It's an unbelievable feeling just to put USA across your chest," he said. "Even if it was just for tryouts or just for practice. To know that you have the opportunity to wear something that says you're playing for the U.S. It feels great."

Congratulations to Luke. I'm not sure anyone deserves it more.

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Source: http://www.cardchronicle.com/2013/7/4/4493536/luke-hancock-selected-as-usa-flag-bearer-at-world-university-games

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Russia urges North Korea to help enable new international talks

MOSCOW (Reuters) - Russia urged North Korea on Thursday to help pave the way for a resumption of international talks and told Pyongyang that ending the standoff over its nuclear program would bring economic benefits.

North Korean First Vice Foreign Minister Kim Kye-Gwan met separately in Moscow with two Russian deputy foreign ministers, Vladimir Titov and Igor Morgulov, the Russian Foreign Ministry said.

Russia "underscored the need for joint efforts aimed at easing tension and creating the conditions for the swift resumption of six-party talks on the basis of principles agreed in the declaration of September 19, 2005," it said in a statement.

That referred to a 2005 aid-for-denuclearization deal that Russia, the United States and other nations say Pyongyang violated by conducting a nuclear test in 2006 and pursuing a uranium enrichment program that would give it a second path to a nuclear weapon, in addition to its plutonium-based program.

Six-party talks involving the two Koreas, the United States, Japan, Russia and China, collapsed in 2008 when the North walked away from the deal. In Beijing last month, Kim repeated an offer for a resumption of the talks, according to Chinese officials. Neither Kim nor the Russia diplomats spoke publicly on Thursday.

The Russian statement about creating conditions for the resumption of the six-party talks seemed to echo U.S. statements that any talks must involve action by the North to show it is moving toward disarmament.

The call for efforts to ease tension signaled that if North Korea wants talks, it must refrain from actions such as nuclear tests and missile launches that have violated U.N. Security Council resolutions.

Russia also held out a carrot.

The diplomats told Kim that "normalizing the situation on the peninsula" would enable Russia and North Korea to step up economic ties and "begin implementation of large-scale international economic projects", the ministry said.

That may have referred in part to a long-discussed pipeline to supply Russian natural gas to South Korea via North Korea, which experts say is highly unlikely to proceed anytime soon because of tension between North and South Korea.

(Writing by Steve Gutterman; Editing by Mark Heinrich)

Source: http://news.yahoo.com/russia-urges-north-korea-help-enable-international-talks-191026376.html

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GOP House leader calls Senate immigration bill a 'pipe dream' (CNN)

Share With Friends: | | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/315645441?client_source=feed&format=rss

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Fed bond-buying could be more aggressive than new timeline: Dudley

By Jonathan Spicer

NEW YORK (Reuters) - The Federal Reserve's asset purchases would be more aggressive than the timeline Chairman Ben Bernanke outlined last week if economic growth and the labor market turn out weaker than expected, the influential head of the New York Fed said on Thursday.

Pushing back hard against market concerns over the withdrawal of quantitative easing, William Dudley stressed in a speech that the newly adopted timeline for reducing the pace of bond buying depends not on calendar dates but on the economic outlook, which remains quite unclear.

Turning to the question of when the Fed will ultimately raise interest rates, Dudley, a close ally of Bernanke, went so far as to say that recent market expectations for an earlier rate rise are "quite out of sync" with the statements and expectations of the policy-making Federal Open Market Committee.

"Economic circumstances could diverge significantly from the FOMC's expectations," Dudley said according to prepared remarks.

"If labor market conditions and the economy's growth momentum were to be less favorable than in the FOMC's outlook ? and this is what has happened in recent years ? I would expect that the asset purchases would continue at a higher pace for longer."

Following a Fed policy meeting last week, Bernanke surprised markets by saying the central bank expected to reduce the $85-billion monthly pace of bond buying later this year and to end the QE3 program altogether by mid-2014, if the economy improves as expected.

Global markets have since fallen sharply, with yields on the 10-year U.S. Treasury spiking to near a two-year high.

Dudley repeated and backed the timeline Bernanke articulated last Wednesday. But he appeared to want to bolster efforts by some of his Fed colleagues this week to calm investors' worries that less Fed accommodation will hurt the slow U.S. and global economic recovery.

The labor market, which the Fed is targeting with QE3, "still cannot be regarded as healthy," Dudley said, adding "there remains a great deal of slack in the economy."

He expects about 2.1 percent Gross Domestic Product growth this year, about the same as it has been since the recession ended in 2009. But Dudley expects that to pick up next year.

Frustrated with fitful U.S. recovery from the Great Recession, the central bank has kept the federal funds rate near zero since late 2008 and has promised to keep it there at least until the unemployment rate falls to 6.5 percent, from 7.6 percent now, as long as inflation stays below 2.5 percent.

Even under the timeline for reducing QE3, "a rise in short-term rates is very likely to be a long way off," Dudley said.

"Not only will it likely take considerable time to reach the FOMC's 6.5 percent unemployment rate threshold, but also the FOMC could wait considerably longer before raising short-term rates," he said.

(Reporting by Jonathan Spicer; Editing by Chizu Nomiyama)

Source: http://news.yahoo.com/fed-bond-buying-could-more-aggressive-timeline-dudley-142837206.html

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Simple two-drug combination proves effective in reducing risk of stroke

June 26, 2013 ? Results of a Phase III clinical trial showed that a simple drug regimen of two anti-clotting drugs -- clopidogrel and aspirin -- lowered the risk of stroke by almost one-third, compared to the standard therapy of aspirin alone, when given to patients who had minor or transient stroke symptoms to prevent subsequent attacks.

Described this week in the New England Journal of Medicine (July 4, 2013 print issue), the clinical trial was conducted at multiple sites in China and designed in partnership with a physician at UC San Francisco.

The trial involved 5,170 people who were hospitalized after suffering minor ischemic strokes or stroke-like events known as transient ischemic attacks, or TIAs, in which blood flow to the brain is briefly blocked. All patients were randomized into two groups and treated for three months with either aspirin alone or aspirin plus clopidogrel, which is marketed as Plavix. The three-month period following stroke is considered the most critical for medical intervention.

Overall, 8.2 percent of patients taking both drugs suffered subsequent strokes in the three months of follow-up compared to 11.7 percent of patients taking aspirin alone.

"The results were striking," said S. Claiborne Johnston, MD, PhD, a professor of neurology and associate vice chancellor of research at UCSF who was a senior author on the study.

The Chinese trial, called CHANCE (Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events), is nearly identical to a National Institutes of Health-sponsored trial that is already enrolling patients in the United States, including at UCSF, called POINT (Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke).

"If POINT confirms CHANCE, then we're done -- the two-drug combination becomes the standard of care," said Johnston. "Anybody with a transient ischemic attack or minor stroke will get clopidogrel plus aspirin."

The POINT trial is important, said Johnston, because genetics, risk factors, and medical practice differences could all lead to differences in trial results in China compared to other countries. Johnston is the principal investigator of the POINT trial.

Stroke in China and the United States

Stroke is a leading cause of death and disability worldwide and is the fourth leading cause of death in the United States.

More than 795,000 people in the United States have strokes every year, and, in 2008 alone, some 133,000 cases were fatal, according to the U.S. Centers for Disease Control and Prevention. Another 300,000 people in the United States have TIAs each year.

Many strokes are minor -- shorter in duration than a full-blown stroke and usually have no lingering health impacts. In China, for instance, about 3 million new strokes occur every year, and about 30 percent of them are minor.

The protocol for the CHANCE trial was developed by Johnston and colleagues at Tiantan Hospital in China. The lead author of the study was Yongjun Wang, MD, of Beijing Tiantan Hospital.

China has many times more people who have strokes every year than the United States because of the size of the population and higher stroke rates, which allowed investigators to screen 41,561 patients in just three years at the 114 clinical sites, and enroll 5,170 patients in the trial.

Increased Risk of Subsequent Stroke

The reason for minor attacks is much the same as a full-blown stroke: a blood clot causes a blockage in the blood vessels that feed oxygen-rich blood to the brain. But in patients with TIAs and many minor strokes, the clot quickly goes away, usually in a few minutes, due to the natural mechanisms in the human body that are designed to deal with such clots.

However, in the weeks following a TIA or minor stroke, there is great risk that another clot will form, causing additional strokes -- potentially major ones. About 10 to 20 percent of people who have a TIA or minor stroke go on to have a subsequent stroke within three months.

Because of this risk, the first 90 days after a stroke or TIA is the most critical window for medical intervention. Currently, people who have minor strokes or TIAs are initially treated with aspirin alone. The purpose of the CHANCE trial was to determine whether clopidogrel with aspirin was more effective than aspirin alone in this intervention.

The drugs basically work the same way. They are "antiplatelet" agents, which target clotting agents found in the bloodstream know as platelets, preventing their aggregation. The combination is used commonly in patients who have heart attacks, but there has been no adequate clinical data to suggest it would work in stroke.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/df9E4AC9RSc/130626184021.htm

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Zebrafish study paves the way for new treatments for genetic disorder

June 26, 2013 ? Scientists from the University of Sheffield have paved the way for new treatments for a common genetic disorder thanks to pioneering research on zebrafish -- an animal capable of mending its own heart.

Charcot Marie Tooth disease (CMT) is the most common genetic disorder affecting the nervous system. More than 20,000 people in the UK suffer from CMT, which typically causes progressive weakness and long-term pain in the feet, leading to walking difficulties. There is currently no cure for CMT.

A research project conducted at the Sheffield Institute for Translational Neuroscience (SITraN) and the MRC Centre for Developmental and Biomedical Genetics (CDBG) by Dr Andrew Grierson and his team has revealed that zebrafish could hold the key to finding new therapeutic approaches to treat the condition.

Dr Grierson said: "We have studied zebrafish with a genetic defect that causes CMT in humans. The fish develop normally, but once they reach adulthood they start to develop difficulties swimming.

"By looking at the muscles of these fish we have discovered that the problem lies with the connections between motor neurons and muscle, which are known to be essential for walking in humans and also swimming in fish."

CMT represents a group of neurodegenerative disorders typically characterised by demyelination (CMT1), a process which causes damage to the myelin sheaths that surround our neurons, or distal axon degeneration (CMT2) of motor and sensory neurons. The distal axon is the terminal where neurotransmitter packages within neurons are docked.

The majority of CMT2 cases are caused by mutations in mitofusin 2 (MFN2), which is an essential gene encoding a protein responsible for fusion of the mitochondrial outer membrane. Mitochondria are known as the cellular power plants because they generate most of the supply of adenosine triphosphate (ATP), which is used as a source of chemical energy.

Dr Grierson said: "Previous work on this disorder using mammalian models such as mice has been problematic, because the mitofusin genes are essential for embryonic development. Using zebrafish we were able to develop a model with an adult onset, progressive phenotype with predominant symptoms of motor dysfunction similar to CMT2.

"Motor neurons are the largest cells in our bodies, and as such they are highly dependent on a cellular transport system to deliver molecules through the long nerve cell processes which connect the spinal cord to our muscles. We already know that defects in the cellular transport system occur early in the development of diseases such as Alzheimer's disease, Motor Neuron Disease and spastic paraplegia. Using our zebrafish model we have found that similar defects in transport are also a key part of the disease process in CMT."

Dr Grierson and his team are now seeking funding to identify new treatments for CMT using the zebrafish model. Because of their size and unique biology, zebrafish are ideal to be used in drug screens for the identification of new therapies for untreatable human conditions.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/AGpvAXqKerU/130626184023.htm

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Defense Of Marriage Act: Supreme Court Crowd Erupts In Cheers Over Ruling

WASHINGTON, DC - JUNE 26: Married couple Michael Knaapen (L) amd John Becker (2nd L) react after hearing the U.S. Supreme Court ruled that the Defense of Marriage Act (DOMA) is unconstitutional at the Supreme Court, June 26, 2013 in Washington, DC. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Mark Wilson/Getty Images)

WASHINGTON, DC - JUNE 26: Married couple Michael Knaapen (L) amd John Becker (2nd L) kiss after hearing the U.S. Supreme Court ruled that the Defense of Marriage Act (DOMA) is unconstitutional at the Supreme Court, June 26, 2013 in Washington, DC. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Mark Wilson/Getty Images)

Michael Knaapen, left, and his husband John Becker, right, embrace outside the Supreme Court in Washington, Wednesday, June 26, 2013, after the court cleared the way for same-sex marriage in California by holding that defenders of California's gay marriage ban did not have the right to appeal lower court rulings striking down the ban. (AP Photo/Charles Dharapak)

NEW YORK, NY - JUNE 26: Richelle Spanover (2nd R) wipes her eye after after the Supreme Court ruled key portions of the Defense of Marriage Act (DOMA) unconstitutional, at the Stonewall Inn on June 26, 2013 in the West Village neighborhood of New York City. The Stonewall Inn became historically important in the Lesbian-Gay-Bigender-Transgender community after playing a key role during the Gay-rights movement of the 1960s and 1970s. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Andrew Burton/Getty Images)

NEW YORK, NY - JUNE 26: Virginia Sin (L) and Gretchen Menter smile after the Supreme Court ruled key portions of the Defense of Marriage Act (DOMA) unconstitutional, at the Stonewall Inn on June 26, 2013 in the West Village neighborhood of New York City. The Stonewall Inn became historically important in the Lesbian-Gay-Bigender-Transgender community after playing a key role during the Gay-rights movement of the 1960s and 1970s. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Andrew Burton/Getty Images)

Edith Windsor, center, accompanied by her attorney Robert Kaplan, right, is greeted by Orie Urami, left, as she arrives at the LGBT Center for a news conference, in New York, Wednesday, June 26, 2013. In a major victory for gay rights, the Supreme Court on Wednesday struck down a provision of a federal law denying federal benefits to married gay couples and cleared the way for the resumption of same-sex marriage in California. (AP Photo/Richard Drew)

David Boies, an attorney arguing in support of gay marriage, speaks to the media after the U.S. Supreme Court overturned the Defense of Marriage Act (DOMA) and declined to rule on the California law Proposition 8 in Washington, D.C., U.S. on Wednesday, June 26, 2013. A divided U.S. Supreme Court gave a landmark victory to the gay-rights movement, striking down a federal law that denies benefits to same-sex married couples and clearing the way for weddings to resume in California. Photographer: Joshua Roberts/Bloomberg via Getty Images

Chris Roe (L) and Roby Chavez (R) celebrate while holding their soon-to-be adopted children as the US Supreme Court ruling is announced on June 26, 2013. The US Supreme Court struck down The Defense of Marriage Act (DOMA) today, and declared that same-sex couples who are legally married deserve equal rights to the benefits under federal law that go to all other married couples. In another ruling, the Supreme Court cleared the way for same-sex marriages to resume in California as the justices, in a prcedural ruling, turned away the defenders of Proposition 8. AFP PHOTO/Josh Edelson (Photo credit should read Josh Edelson/AFP/Getty Images)

Edith Windsor arrives at the LGBT Center for a news conference, in New York, Wednesday, June 26, 2013. In a major victory for gay rights, the Supreme Court on Wednesday struck down a provision of a federal law denying federal benefits to married gay couples and cleared the way for the resumption of same-sex marriage in California. (AP Photo/Richard Drew)

Edith Windsor reacts during a news conference at the LGBT Center, in New York, Wednesday, June 26, 2013. In a major victory for gay rights, the Supreme Court on Wednesday struck down a provision of a federal law denying federal benefits to married gay couples and cleared the way for the resumption of same-sex marriage in California. (AP Photo/Richard Drew)

Kris Perry, second from right, kisses her partner Sandy Stier outside the Supreme Court in Washington, Wednesday, June 26, 2013, after the court cleared the way for the resumption of same-sex marriage in their home state of California. From left are, plaintiffs Jeff Zarrillo, and his partner Paul Katami, attorney David Boies, plaintiffs Sandy Stier and Kris Perry, and attorney Ted Boutrous. (AP Photo/J. Scott Applewhite)

John Lewis, left, and Stuart Gaffney embrace outside San Francisco's City Hall shortly before the U.S. Supreme Court ruling cleared the way for same-sex marriage in California on Wednesday, June 26, 2013. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. (AP Photo/Noah Berger)

Sandy Stier, center, and her partner Kris Perry, right, plaintiffs in Hollingsworth v. Perry, the California Proposition 8 case, meets with reporters outside the Supreme Court in Washington, Wednesday, June 26, 2013, after the court's 5-4 decision that cleared the way for the resumption of same-sex marriage in their home state of California. Gesturing at far left is fellow plaintiff Jeff Zarrillo. (AP Photo/J. Scott Applewhite)

WASHINGTON, DC - JUNE 26: American University students Sharon Burk (L) and Mollie Wagoner (R) embrace after hearing that the U.S. Supreme Court ruled that the Defense of Marriage Act (DOMA) is unconstitutional at the Supreme Court, June 26, 2013 in Washington, DC. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Mark Wilson/Getty Images)

John Lewis, left, and his partner Stuart Gaffney embrace as they react next to Andrea Shorter after the Supreme Court decision at the office of San Francisco Mayor Ed Lee at City Hall in San Francisco, Wednesday, June 26, 2013. The Supreme Court on Wednesday struck down a provision of a U.S. law denying federal benefits to married gay couples and cleared the way for the resumption of same-sex marriage in the state of California. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. (AP Photo/Jeff Chiu)

SAN FRANCISCO, CA - JUNE 26: Same-sex couple Jewelle Gomez (R) and Diane Sabin react upon hearing the U.S. Supreme Court's rulings on gay marriage in City Hall June 26, 2013 in San Francisco, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Justin Sullivan/Getty Images)

Gay rights activist Bryce Romero, who works for the Human Rights Campaign, offers an enthusiastic high-five to visitors getting in line to enter the Supreme Court on a day when justices are expected to hand down major rulings on two gay marriage cases that could impact same-sex couples across the country, in Washington, Wednesday, June 26, 2013. (AP Photo/J. Scott Applewhite)

Gay rights activist Bryce Romero, who works for the Human Rights Campaign, offers an enthusiastic high-five to visitors getting in line to enter the Supreme Court on a day when justices are expected to hand down major rulings on two gay marriage cases that could impact same-sex couples across the country, in Washington, Wednesday, June 26, 2013. (AP Photo/J. Scott Applewhite)

WASHINGTON, DC - JUNE 26: Attorney David Boise (C) speaks while flanked by plantiff couples Paul Katami, (L), Jeff Zarillo (2nd L), Sandy Steier (2nd R) and Kris Perry (R) after the U.S. Supreme Court ruled that part of the Defense of Marriage Act (DOMA) is unconstitutional at the Supreme Court, June 26, 2013 in Washington, DC. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Mark Wilson/Getty Images)

Plaintiffs in Hollingsworth v. Perry, the California Proposition 8 case, react on steps of the Supreme Court in Washington, Wednesday, June 26, 2013, after justices cleared the way for the resumption of same-sex marriage in California. From left are, Jeff Zarrillo, and his partner Paul Katami, attorney David Boies, and Sandy Stier and her partner Kris Perry. (AP Photo/J. Scott Applewhite)

Michael Knaapen (L) and his husband John Becker react outside the US Supreme Court in Washington DC on June 26, 2013. The US Supreme Court on Wednesday struck down a controversial federal law that defines marriage as a union between a man and a woman, in a major victory for supporters of same-sex marriage.The Defense of Marriage Act (DOMA) had denied married gay and lesbian couples in the United States the same rights and benefits that straight couples have long taken for granted. AFP PHOTO / MLADEN ANTONOV (Photo credit should read MLADEN ANTONOV/AFP/Getty Images)

WASHINGTON, DC - JUNE 26: Chase Hardin hugs friend Kai Neander on the steps of the Supreme Court after favorable rulings were issued in same sex marriage cases June 26, 2013 in Washington, DC. The high court ruled to strike down DOMA and determined the California's proposition 8 ban on same-sex marriage was not properly before them, declining to overturn the lower court's striking down of the law. (Photo by Win McNamee/Getty Images)

WASHINGTON, DC - JUNE 26: Gay rights supporter Jay Norris, of New York City, holds a U.S. flag outside the U.S. Supreme Court building on June 26, 2013 in Washington, DC. The high court is expected to rule on the DOMA and Prop 8 gay marriage cases. (Photo by Win McNamee/Getty Images)

WEST HOLLYWOOD, CA - JUNE 26: Martha Acevedo, 25, celebrates the Supreme Court ruling after a watch party at Equality California, a non-profit civil rights organization that advocates for the rights of LGBT people in California, on June 26, 2013 in West Hollywood, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Kevork Djansezian/Getty Images)

Ellen Pontac, left, and her wife Shelly Bailes, celebrate in Sacramento, Calif., after the U.S. Supreme Court's ruling on gay marriage in California, Wednesday, June 26, 2013. The 5-4 decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples, like Pontac and Bailes, from receiving tax, health and pension benefits. (AP Photo/Rich Pedroncelli) will now have the same (AP Photo/Rich Pedroncelli)

Attendees at a watch party in Miami celebrate after the U.S. Supreme Court's ruling on gay marriage in California Wednesday, June 26, 2013. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. (AP Photo/Wilfredo Lee)

Julia Tate, left, kisses her wife, Lisa McMillin, as they read results of Supreme Court decisions regarding gay rights on Wednesday, June 26, 2013, in Nashville, Tenn. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. McMillin holds the couple's son, Luke. (AP Photo/Mark Humphrey)

Juan Talavera, right, kisses his partner Jeff Ronci after the announcement of the U.S. Supreme Court's ruling at a watch party in Miami, Wednesday, June 26, 2013. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. (AP Photo/Wilfredo Lee)

Renata Moreira, right, and partner Lori Bilella cheer after the U.S. Supreme Court's ruling on gay marriage in California, at San Francisco's City Hall on Wednesday, June 26, 2013. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. The couple plans to marry. (AP Photo/Noah Berger)

WEST HOLLYWOOD, CA - JUNE 26: Erica Ikeda (C), 26, and Jessica Parral (R), 24, react to the Supreme Court ruling at a watch party at Equality California, a non-profit civil rights organization that advocates for the rights of LGBT people in California, on June 26, 2013 in West Hollywood, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Kevork Djansezian/Getty Images)

WEST HOLLYWOOD, CA - JUNE 26: Brandon Benoit (C) hugs Martha Acevedo (L), 25, and Briana Castaneda, 23, as they celebrate the Supreme Court ruling at a watch party at Equality California, a non-profit civil rights organization that advocates for the rights of LGBT people in California, on June 26, 2013 in West Hollywood, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Kevork Djansezian/Getty Images)

WEST HOLLYWOOD, CA - JUNE 26: People celebrate in the street after the Supreme Court ruling at a watch party at Equality California, a non-profit civil rights organization that advocates for the rights of LGBT people in California, on June 26, 2013 in West Hollywood, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Kevork Djansezian/Getty Images)

SAN FRANCISCO, CA - JUNE 26: Supporters of same-sex marriage cheer as they learn results of the U.S. Supreme Court's rulings on gay marriage in City Hall June 26, 2013 in San Francisco, United States. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Justin Sullivan/Getty Images)

SAN FRANCISCO, CA - JUNE 26: Same-sex couple Sue Rochman (L) and Robin Romdalvik celebrate upon hearing the U.S. Supreme Court's rulings on gay marriage in City Hall June 26, 2013 in San Francisco, United States. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Justin Sullivan/Getty Images)

Gay rights activists reacts outside the US Supreme Court building in Washington DC on June 26, 2013, after the court ruling on California's Proposition 8, the controversial ballot initiative that defines marriage as between a man and a woman. AFP PHOTO / MLADEN ANTONOV (Photo credit should read MLADEN ANTONOV/AFP/Getty Images)

WEST HOLLYWOOD, CA - JUNE 26: Erica Ikeda (C), 26, and her friends react to the Supreme Court ruling at a watch party at Equality California, a non-profit civil rights organization that advocates for the rights of LGBT people in California, on June 26, 2013 in West Hollywood, California. The high court struck down the Defense of Marriage Act (DOMA) and ruled that supporters of California's ban on gay marriage, Proposition 8, could not defend it before the Supreme Court. (Photo by Kevork Djansezian/Getty Images)

John Lewis, left, gets a kiss from his partner Stuart Gaffney as they embrace after the Supreme Court cleared the way for same-sex marriage in California at the office of San Francisco Mayor Ed Lee at City Hall in San Francisco, Wednesday, June 26, 2013. The justices issued two 5-4 rulings in their final session of the term. One decision wiped away part of a federal anti-gay marriage law that has kept legally married same-sex couples from receiving tax, health and pension benefits. The other was a technical legal ruling that said nothing at all about same-sex marriage, but left in place a trial court's declaration that California's Proposition 8 is unconstitutional. (AP Photo/Jeff Chiu)

WASHINGTON, DC - JUNE 26: Plaintiff couple Sandy Stier (C) and Kris Perry (L) arrive for their Proposition 8 case before the U.S. Supreme Court on June 26, 2013 in Washington, DC. The high court is expected to rule on the DOMA and Prop 8 gay marriage cases. (Photo by Win McNamee/Getty Images)

WASHINGTON, DC - JUNE 26: Gay rights supporters Brian Sprague (L) and Charlie Ferrusi, from Albany, New York, hold a Human Rights flag outside U.S. Supreme Court building on June 26, 2013 in Washington, DC. The high court is expected to rule on the DOMA and Prop 8 gay marriage cases. (Photo by Win McNamee/Getty Images)

WASHINGTON, DC - JUNE 26: Gay rights supporter Vin Testa waves a rainbow flag outside the U.S. Supreme Court building on June 26, 2013 in Washington, DC. The high court is expected to rule on the DOMA and Prop 8 gay marriage cases. (Photo by Win McNamee/Getty Images)

Gay rights activists gather outside the US Supreme Court building in Washington, DC on June 26, 2013. The US Supreme Court on Wednesday struck down a controversial federal law that defines marriage as a union between a man and a woman, in a major victory for supporters of same-sex marriage.The Defense of Marriage Act (DOMA) had denied married gay and lesbian couples in the United States the same rights and benefits that straight couples have long taken for granted. AFP PHOTO / MLADEN ANTONOV (Photo credit should read MLADEN ANTONOV/AFP/Getty Images)

American University students Sharon Burk, left, and Molly Wagner, embrace outside the Supreme Court in Washington, Wednesday, June 26, 2013, after the court cleared the way for same-sex marriage in California by holding that defenders of California's gay marriage ban did not have the right to appeal lower court rulings striking down the ban. (AP Photo/Charles Dharapak)

Arriving at the Supreme Court in Washington, Wednesday, June 26, 2013, on a final day for decisions in two gay marriage cases are plaintiffs in the California Proposition 8 case, from left, Paul Katami, his partner Jeff Zarrillo, and Sandy Stier and her partner Kris Perry. (AP Photo/J. Scott Applewhite)

Michael Knaapen, left, and his husband John Becker, right, embrace outside the Supreme Court in Washington, Wednesday, June 26, 2013 after the court struck down a federal provision denying benefits to legally married gay couples. (AP Photo/Charles Dharapak)

American University students Sharon Burk, left, and Molly Wagner participate in a rally for rights for gay couples in front of the Supreme Court in Washington, Wednesday, June 26, 2013, after the court cleared the way for same-sex marriage in California by holding that defenders of California's gay marriage ban did not have the right to appeal lower court rulings striking down the ban. (AP Photo/Charles Dharapak)

Supporters of gay marriage embrace outside the Supreme Court in Washington, Wednesday, June 26, 2013, after the court cleared the way for same-sex marriage in California by holding that defenders of California's gay marriage ban did not have the right to appeal lower court rulings striking down the ban. (AP Photo/Charles Dharapak)

Sen. Richard Blumenthal (D-Conn.) spotted in the crowd during the SCOTUS decisions on June 26

Source: http://www.huffingtonpost.com/2013/06/26/defense-of-marriage-act-supreme-court_n_3454846.html

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Miesha Tate to pose nude in ESPN the Magazine

UFC bantamweight Miesha Tate is joining the ranks of MMA fighters who have posed nude in ESPN the Magazine's Body Issue. The magazine announced today that Tate will appear in the yearly issue that shows off athletes' bodies. It will hit newsstands on July 12.

Tate's opposing coach on the upcoming season of "The Ultimate Fighter," UFC women's bantamweight champion Ronda Rousey, was on last season's cover. Both women appearing in the magazine will give them one more thing to trash talk about as they film the TUF that will air in September.

[Related: Mets' Matt Harvey to flaunt curves in 'Body Issue']

UFC president Dana White said the filming is filled with their squabbles every day.

"It's going exactly the way you thought it would be going: bad," White said. "Dead serious. Miesha and Ronda hate each other. It's literally crazy drama every day. It's irritating."

Other fighters who have been in the Body Issue include Jon Jones and Gina Carano.

Related coverage on Yahoo! Sports:
? Native American fighter Dan Hornbuckle more than a face in the crowd
? Is Chris Weidman the one to take out Anderson Silva?
? Ricardo Lamas depending on family to get over disappointing pursuit of UFC belt

Source: http://sports.yahoo.com/blogs/mma-cagewriter/miesha-tate-pose-nude-espn-magazine-201403709.html

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Digital Workshop: Searching in Windows 8

Holland America Blog Has Just Posted the Following:

Special thanks to Zuiderdam?s Techspert Krista who posted this on HAL?s Digital Workshop blog. Today I wanted to share some hints about searching in Windows 8. I loved searching in Windows 7. It was a fast and easy way to find anything I needed. Searching in Windows 8 is a little different, but just as [...]

Click here to view the article.

Source: http://www.cruise-addicts.com/forums/f43/digital-workshop-searching-windows-8-a-206718-new/

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Stars fire GM Joe Nieuwendyk after 4 seasons

DALLAS (AP) ? The Dallas Stars fired general manager Joe Nieuwendyk on Sunday after four seasons, two coaches and no playoff appearances.

The dismissal came the day after Dallas completed a 22-22-4 season. The Stars missed the playoffs for the fifth season in a row.

Owner Tom Gaglardi said in a statement that Nieuwendyk represented the Stars "extremely well" and "helped put pieces in place that will once again turn this team into a contender." He added, however, the team must go "in a different direction with our intentions set on returning to the elite" of the NHL.

The team is to announce its new GM on Monday. While the Stars have not said who it is, Gaglardi is "confident we have found the right general manager to return us to the pathway of success."

The team has refused to comment on reports that Jim Nill, Detroit's longtime assistant GM, will get the job.

The future of coach Glen Gulutzan wasn't addressed by the team in its statement. Dallas holds an option for a third season for Gulutzan, who is 64-57-9 in his two seasons after ending the lockout-shortened season with a 3-0 home loss to Detroit. The Stars dropped their last five games and won only once in their last seven after a five-game winning streak.

When asked about his job after Saturday night's game, Gulutzan said that wasn't under his control. He did praise Nieuwendyk.

"All I can say is that Joe's been tremendous for me. I think he's done a hell of a job," Gulutzan said. "You can see with our farm team and the young guys that we have here."

As a player in Dallas, Nieuwendyk won the Conn Smythe Award as playoff MVP in 1999 when the Stars won their only Stanley Cup.

When hired by Nieuwendyk two years ago to replace the fired Marc Crawford, the 41-year-old Gulutzan had never coached in the NHL. Gulutzan had been a successful minor league coach.

Crawford was hired following Dave Tippett's firing in 2009, after the Stars missed the playoffs a year after making it to the Western Conference finals. Tippett later that year replaced Wayne Gretzky as coach in Phoenix and led the Coyotes to the playoffs. He was honored as the league's top coach.

The Stars weren't eliminated from the playoff chase until Thursday night. They stayed in postseason contention even after longtime captain Brenden Morrow was traded, a week before 41-year-old points leader Jaromir Jagr and Derek Roy were dealt at the trading deadline.

Dallas got several young players and extra draft picks in those deals. Within days after Jagr and Roy were traded, the young Stars went on a season-best five-game winning streak.

Morrow waived his no-trade clause to go to Pittsburgh, which entered the playoffs as the No. 1 seed in the Eastern Conference. Morrow's rookie season in Dallas was 1999-2000, when the Stars were the Stanley Cup runner-up a year after their title.

Source: http://news.yahoo.com/stars-fire-gm-joe-nieuwendyk-4-seasons-170756655.html

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French electronic duo Daft Punk snatches top spot in UK charts

LONDON (Reuters) - French electronic duo Daft Punk notched up their first number one in Britain's official singles charts on Sunday, dislodging London drum'n'bass quartet Rudimental who were pushed into the number two spot.

Daft Punk's song "Get Lucky", featuring the guest vocals of Pharrell Williams and Nile Rodgers on guitar, had entered the chart the previous week in the number three spot.

It racked up sales of 155,000 in the past week, the Official Charts Company said, the biggest one-week sales tally of the year.

"Get Lucky" is the lead single from the French duo's upcoming fourth album "Random Access Memories" and is the outfit's third biggest hit behind "One More Time" (2000) and "Around The World" (1997).

In the album charts, Canadian crooner Michael Buble's "To Be Loved" held on to the number one spot for a second week.

"To Be Loved" is the follow-up to Buble's festive album "Christmas", which has sold 1.8 million copies in Britain since its release in October 2011.

"Tape Deck Heart", an album from singer-songwriter Frank Turner who performed during the warm-up to the 2012 Olympic Games opening ceremony, went straight into the number two spot.

Meanwhile, "#willpower", a new album from will.i.am, debuted at number three.

(Reporting By Andrew Osborn)

Source: http://news.yahoo.com/french-electronic-duo-daft-punk-snatches-top-spot-192607481.html

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Source: http://rss.news.yahoo.com/rss/weightloss

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Ban on strapless dresses for prom angers N.J. parents

By Victoria Cavaliere

(Reuters) - A New Jersey principal's ban on strapless dresses at a junior high school dance because they would be "distracting" to boys has enraged parents, who called on Tuesday for its reversal on the grounds it violates their daughters' constitutional rights.

The dress code shreds the 14th Amendment right to equal protection since girls for the past six years have been wearing sleeveless fashions to the dance at Readington Middle School in Readington Township, New Jersey, said parent Charlotte Nijenhuis.

Parents petitioned the school board on Tuesday to overturn the policy before the June 12th dance.

The school's principal, Sharon Moffat, said in a letter last month that a "dress with straps" was the only style that would be allowed.

Nijenhuis said she called Moffat to ask why strapless dresses had been forbidden. "She told me, ?It is because it's distracting to boys and inappropriate','" Nijenhuis said.

Moffat did not respond to a Reuters request for comment.

Another parent, Michelle D'Amico, said she was "livid" that her 14-year-old daughter was being prevented from wearing the same strapless dress that her older daughter had worn six years ago. "It's completely unjust," D'Amico said.

The Readington Township School District said in a statement on Tuesday that it "has a policy regarding dress code which is being universally applied to the school day and school events. We regret that a small number of families are upset by this and we welcome their input and communication."

At least one student, Claudine Nijenhuis, 14, said she planned to defy the ban and press her right to bare arms.

"Basically by saying 'it distracts the boys' you're also saying that it is our fault on how they control their own behavior," the teenager wrote in a letter to the principal. "I will still be attending the dinner dance function, but I will also be wearing a dress with no straps."

(Editing by Barbara Goldberg)

Source: http://news.yahoo.com/jersey-parents-demand-girls-bare-arm-strapless-dresses-022245280.html

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Ford, KB Home partner on green-living concepts with ZeroHouse 2.0

Home Is Where the Hybrid Is: KB Home Features Ford's MyEnergi Lifestyle

• Collaboration pairs Ford C-MAX Energi and other energy-efficient technologies with KB Home's ZeroHouse 2.0 model home to showcase affordable sustainable living
• KB Home to feature Ford's MyEnergi Lifestyle? in ZeroHouse 2.0 in San Marcos, Calif.
• ZeroHouse 2.0 represents the next generation of energy-efficient home design that can help lower cost of home ownership compared to a typical resale home. A fully optioned ZeroHouse 2.0 could entirely eliminate monthly electricity charges
• With a starting price of $29,995, Ford C-MAX Energi is America's most affordable plug-in hybrid vehicle

DEARBORN, Mich. & SAN DIEGO, April 19, 2013 ? Ford Motor Company and KB Home (NYSE: KBH) today announce that products from the Ford-led initiative MyEnergi Lifestyle? will be featured in the homebuilder's ZeroHouse 2.0 model home in San Marcos, Calif., and potentially in additional KB Home markets.

The relationship between these two innovative leaders is intended to raise awareness of MyEnergi Lifestyle benefits and provide a showcase for electric-powered vehicles, solar power systems and smart appliances. The initiative will demonstrate how the typical American family can potentially save money while reducing their impact on the environment by combining a highly efficient home design with the latest in smart home technology and an affordable plug-in hybrid vehicle.

MyEnergi Lifestyle works by leveraging technology so key energy-consuming devices in a home use less energy, while also shifting energy usage to less expensive periods. At night, for example, when energy costs are lower, a smart refrigerator can perform high-energy tasks like ice making or defrosting ? just as Ford's plug-in vehicles do with recharging.

At an event today in San Marcos, Ford's all-new C-MAX Energi was on display and plugged into ZeroHouse 2.0's built-in electric vehicle charge station, which is engineered to charge the vehicle during off-peak hours for maximum cost efficiency. C-MAX Energi boasts an impressive 100 MPGe combined, according to the EPA, plus ? unlike others in the segment ? returns "real car" performance with up to 195 horsepower, engaging driving dynamics and a quiet interior. With a starting price of $29,995, C-MAX Energi is America's most affordable plug-in hybrid.

"KB Home is a leader in incorporating state-of-the-art sustainable building practices, and we're thrilled to feature MyEnergi Lifestyle products in these homes," said Mike Tinskey, Ford global director of vehicle electrification and infrastructure. "The home and vehicle share a common 'fuel' called electricity, now more than ever. Our commitment to sustainability compels us to work collaboratively to find technology solutions that are greater than the sum of the parts."

The future of net-zero energy
ZeroHouse 2.0 continues a national rollout of the net-zero energy home options KB Home began in fall 2011. The ZeroHouse 2.0 in San Marcos pushes the envelope even more, as it's the first WaterSense-labeled home built in San Diego County, and includes both a comprehensive Schneider Electric Wiser? Home Management System and all-new Whirlpool smart appliances that incorporate Whirlpool? 6th Sense Live? technology. The Wiser Home Management System allows homeowners to monitor energy consumption, and provides automation control via a Web-based portal or mobile application. This marks the first time these innovative products have been used by a production homebuilder.

Whirlpool's smart products allow homeowners to monitor and program their appliances through wireless networks, providing greater convenience and control over energy consumption. With Whirlpool 6th Sense Live, homeowners can set their appliances so their highest energy consumption activities happen at times when electricity rates are lowest. They can also receive alerts about the status of their smart appliances ? all from their smartphones or computers.

"We're so pleased to announce our new relationship with Ford, and to have the opportunity to use our innovative new ZeroHouse 2.0 as a true model for an energy-efficient and sustainable lifestyle that we know many of today's consumers desire to achieve," said Jeff Mezger, president and CEO, KB Home. "We continue to refine our ZeroHouse 2.0 options and benefits by further developing and incorporating some of the latest new home building practices and technologies available today."

The higher efficiency of ZeroHouse 2.0 is the result of a whole-home approach ? from the inside out ? that includes additional insulation; upgraded HVAC systems; dual-pane, low-emitting windows; and roof-mounted solar panels by SunPower. Additionally, a WaterSense-labeled home is designed to use 20 percent less water than a typical new home. For a family of four, that's a difference of about 50,000 gallons of water a year compared to a typical home, or enough for nearly 2,000 loads of laundry and as much as $600 in annual utility bills.

At today's event students from San Marcos Middle School and local officials learned firsthand how much money can potentially be saved by living in an energy-efficient ZeroHouse 2.0 home. The students toured the home to learn about the efficiency features included, then watched as a dump truck load of schoolyard dodge balls was spilled out, symbolizing the amount of water a WaterSense-labeled home saves in less than a week compared to a typical new or resale home. KB Home announced it would make a cash donation to the school, equivalent to a year's worth of energy and water savings enjoyed by a family living in the ZeroHouse 2.0 home when compared to a typical resale home.

History of MyEnergi Lifestyle
The Ford-led MyEnergi Lifestyle collaboration is comprised of leaders in the home appliance, solar power and power management industries, and includes Eaton (NYSE: ETN), SunPower (NASDAQ: SPWR) and Whirlpool (NYSE: WHR). Additional featured companies include semiconductor provider Infineon (FSE: IFX/OTCQX: IFNNY) and Nest Labs, with its latest learning thermostat represented in the research and implementation phase of the collaboration.

In January Ford released results of a Georgia Institute of Technology computer model that calculated the electricity usage of a typical single family in their home for one year, and the associated savings with moving to an energy-efficient lifestyle. The cumulative results predict a 60 percent reduction in energy costs and more than 9,000 kg of CO2 (a 55 percent reduction) saved. If every home in the U.S. were to implement these energy-saving technologies, it would be the equivalent of taking all the homes in California, New York and Texas ? 32 million homes ? off the power grid.

# # #

About Ford Motor Company
Ford Motor Company, a global automotive industry leader based in Dearborn, Mich., manufactures or distributes automobiles across six continents. With about 171,000 employees and 65 plants worldwide, the company's automotive brands include Ford and Lincoln. The company provides financial services through Ford Motor Credit Company. For more information regarding Ford and its products worldwide, please visit http://corporate.ford.com.

About KB Home
KB Home is one of the largest and most recognized homebuilding companies in the United States. Since its founding in 1957, the company has built more than half a million quality homes. KB Home's signature Built to Order? approach lets each buyer customize their new home from lot location to floor plan and design features. In addition to meeting strict ENERGY STAR? guidelines, all KB homes are highly energy efficient to help lower monthly utility costs for homeowners, which the company demonstrates with its proprietary KB Home Energy Performance Guide? (EPG?). A leader in utilizing state-of-the-art sustainable building practices, KB Home was named the #1 Green Homebuilder in the most recent study by Calvert Investments and the #1 Homebuilder on FORTUNE magazine's 2011 World's Most Admired Companies list. Los Angeles-based KB Home was the first homebuilder listed on the New York Stock Exchange, and trades under the ticker symbol "KBH." For more information about KB Home's new home communities, call 888-KB-HOMES or visit www.kbhome.com.

Source: http://green.autoblog.com/2013/04/23/ford-kb-home-partner-zerohouse-2/

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